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Thursday, February 15, 2018

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SLIDESHOW 



NUZZEL “NEXT” story archive for 15Feb18 Alzheimer’s Cure in sight? 


Health concerns for the 55+ population may be topped by two primary fears: 1) cancer and 2) Alzheimer’s.  This issue of WEEKENDERhttp://docdro.id/OmWuvjT ▶ archives the second topic with the following data SOURCED ▶ https://goo.gl/8i3irf

“More than four million Americans suffer from Alzheimer’s, and as many as twenty million have close relatives or friends with the disease.” Revolutionizing the way we perceive and live with Alzheimer’s, Joanne Koenig Coste offers a practical approach to the emotional well-being of both patients and caregivers that emphasizes relating to patients in their own reality. Her accessible and comprehensive method, which she calls habilitation, works to enhance communication between care partners and patients and has proven successful with thousands of people living with dementia. Learning to Speak Alzheimer’s also offers hundreds of practical tips, including how to:

· cope with the diagnosis and adjust to the disease’s progression
· help the patient talk about the illness
· face the issue of driving
· make meals and bath times as pleasant as possible
· adjust room design for the patient’s comfort
· deal with wandering, paranoia, and aggression

▶ SOURCED from: Sai Janani Ganesan, Postdoctoral Scholar at UCSF, on Quora If you regularly read the news—either the politics or the science and technology section, you have read at least a couple of articles in the last year on Alzheimer’s disease (AD) or more broadly, dementia. Alzheimer’s disease (AD) is a neurodegenerative disease and is the leading cause of dementia—a syndrome or a condition that manifests as a group of symptoms that affect cognitive and behavioral skills due to death of neurons, arising from a multitude of largely unknown causes (with the exception of genetic abnormalities). There aren’t any medications available today that either slow or stop neuronal damage, the drugs available in the market are involved in only marginally improving symptoms and are highly patient dependent. With a total number of affected individuals predicted to increase to 13 million in the US and over 100 million worldwide by 2050, and skyrocketing costs for dementia care (currently at $259 billion (2017) and expected to grow to $1 trillion by 2050), it is safe to call dementia one of the biggest public health problems of our times. “An experimental treatment completely reversed Alzheimer's disease in mice by reducing the levels of a single enzyme in the animals' brains. The results further bolster the theory that amyloid plaques are at the root of this mysterious brain disease, and that addressing these plaques could lead to an eventual cure for Alzheimer's. “The study, published February 14 in the Journal of Experimental Medicine, found that slowly reducing levels of the enzyme BACE1 in mice as they aged either prevented or reversed the formation of amyloid plaques in the brain, a hallmark sign of Alzheimer's disease.” MORE: Blocking enzyme 'dramatically reverses' Alzheimer's in mice
Amyloid plaques, formed when bits of protein clump together in the brain, are found in high amounts in Alzheimer's patients. BACE1 is a protein that naturally forms in the brain and helps produce beta-amyloid peptide, a protein also involved with brain plaque formation.


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▶ SLIDESHOW   ▶ NUZZEL “NEXT” story archive for 15Feb18 ▶ Alzheimer’s Cure in sight?   ▶ Health concerns for the 5...

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