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What About Lymphocytes?


The photopheresis procedures that I am receiving at COH for the next several weeks (until the GVHD skin rash is gone), is explained by the following LINKS and experts.

Essentially, this is an effort to combat lymphocytes in my blood that are correctly handling their assignment to attack "foreign" bodies, but the problem is my blood is now sourced from my donor and the lymphocytes have been tricked into thinking that my skin (perhaps other organs, too) are foreign. Actually, all my blood tests indicate that the reaction is limited to the skin rash and that condition is sustaining, but improving at this time.


From the experts: "A lymphocyte is a type of white blood cell in the vertebrate immune system. By their appearance under the light microscope, there are two broad categories of lymphocytes, namely the large granular lymphocytes and the small lymphocytes. Functionally distinct subsets of lymphocytes correlate with their appearance. Most, but not all large granular lymphocytes are more commonly known as the natural killer cells (NK cells). The small lymphocytes are the T cells and B cells. Lymphocytes play an important and integral role in the body's defenses. An average human body contains about 1012 lymphoid cells, and the lymphoid tissue as a whole represents about 2% of the total body weight."

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