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Showing posts from September 5, 2010

DNA damage, repair may be key to cancer and recovery

DNA damage, repair may be key to cancer and recovery: DUARTE, Calif. — City of Hope scientists have found a key to a protein’s ability to repair and make new copies of DNA, which may lead to a greater understanding of how genetic damage contributes to diseases such as cancer. The study is available online now in advance of print publication in Nature Chemical Biology. Story dated 23 Aug 2010

Binghui Shen, Ph.D., professor and associate chair of the Department of Cancer Biology in Beckman Research Institute of City of Hope, led a team of researchers who discovered a new way that cells modify a protein called flap endonuclease 1, or FEN1, to control its activity. FEN1 plays important roles in proper DNA duplication, repair and clean up — all important functions to keeping cells healthy.
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